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K0131
Sigma
Monoclonal Anti-c-kit/SCF Receptor antibody produced in mouse
clone K44.2, purified immunoglobulin, buffered aqueous solution
| Synonym: | Anti-SCF Receptor |
| MDL number: | MFCD00282320 |
Description
| Immunogen | recombinant human c-kit/SCF receptor produced in transfected CHO cells. |
| Specificity | The antibody can displace receptor-bound SCF and inhibit SCF-induced proliferation of human cells such as M07e and TF-1. |
| Physical form | Solution, 0.2 μm filtered, in phosphate buffered saline, pH 7.4. |
Properties
| antibody form | purified immunoglobulin |
| clone | K44.2 (monoclonal) |
| form | buffered aqueous solution |
| species reactivity | human |
| application(s) | flow cytometry: suitable |
| neutralization: 0.1 μg/mL using TF-1 cells | |
| isotype | IgG1 |
| Gene Information | human ... KITLG(4254) |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
| WGK Germany | 3 |
References
| reference | Blechman, J.M., et al., The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction. Cell 80, 103-113, (1995) Abstract |
| Lev, S., et al., Interspecies molecular chimeras of kit help define the binding site of the stem cell factor. Mol. Cell. Biol. 13, 2224-2234, (1993) Abstract |
